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Drug interactions between Intelence and Tivicay

Results for the following 2 drugs:
Intelence (etravirine)
Tivicay (dolutegravir)

Interactions between your drugs

Major

etravirine dolutegravir

Applies to: Intelence (etravirine) and Tivicay (dolutegravir)

Etravirine may reduce the blood levels of dolutegravir, which may make the medication less effective in treating HIV infection. You should not be taking these medications together unless you are also receiving either atazanavir/ritonavir, darunavir/ritonavir or lopinavir/ritonavir in your HIV regimen, since adding these agents helps to diminish the interaction between etravirine and dolutegravir. Contact a healthcare professional if you have any questions or concerns, and seek immediate medical attention if your condition worsens or you develop new infections during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

etravirine food

Applies to: Intelence (etravirine)

Etravirine should always be administered following a meal. Food enhances the levels of etravirine in your body. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

dolutegravir food

Applies to: Tivicay (dolutegravir)

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

For clinical details see professional interaction data.

Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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