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Drug interactions between Gilotrif and Tarceva

Results for the following 2 drugs:
Gilotrif (afatinib)
Tarceva (erlotinib)

Interactions between your drugs

There were no interactions found in our database between Gilotrif and Tarceva. However, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Gilotrif

A total of 133 drugs (445 brand and generic names) are known to interact with Gilotrif.

Tarceva

A total of 231 drugs (1009 brand and generic names) are known to interact with Tarceva.

Drug and food interactions

Moderate

erlotinib food

Applies to: Tarceva (erlotinib)

Erlotinib should be taken on an empty stomach 1 hour before or 2 hours after a meal and at the same time each day unless otherwise directed by your doctor. You should also avoid grapefruit and grapefruit juice while taking erlotinib. Food and grapefruit can raise the levels of erlotinib in your body and lead to increased side effects. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

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Moderate

afatinib food

Applies to: Gilotrif (afatinib)

Food may reduce the absorption of afatinib, which may lead to lower blood levels of the medication and possibly reduced effectiveness. You should take afatinib at least 1 hour before or 2 hours after a meal.

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Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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