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Drug Interactions between gepirone and Uritact DS

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

methylene blue gepirone

Applies to: Uritact DS (hyoscyamine / methenamine / methylene blue / phenyl salicylate) and gepirone

Using gepirone together with methylene blue is not recommended as it can significantly increase the risk of a potentially life-threatening problem called serotonin syndrome. Immediate medical attention is required if you experience any of the following as they may be signs or symptoms of this medical condition: nausea, vomiting, and diarrhea; agitation; confusion; fast heartbeat; sweating; flushing; seizures; hallucinations; coma; blood pressure changes; shaking, stiff muscles, or muscle twitching; dizziness; high body temperature; and/or loss of coordination. In general, it is advisable to wait at least 14 days after you stop using methylene blue or similar medications before you start using gepirone or vice versa. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

gepirone food

Applies to: gepirone

Food helps with the absorption of gepirone into the blood stream. You should take this medication with food at about the same time every day. You should not consume grapefruit or grapefruit products while taking this medication as they can increase the blood levels of gepirone in your body, putting you at a higher risk of serious side effects like serotonin syndrome or a change in the electrical activity of your heart called QT prolongation. Seek immediate medical attention if you experience any of the following signs or symptoms of these potentially life-threatening side effects: irregular or fast heartbeat, dizziness, lightheadedness, fainting, agitation, confusion, sweating, flushing, changes in blood pressure, seizures, hallucinations, or a loss of coordination. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

hyoscyamine food

Applies to: Uritact DS (hyoscyamine / methenamine / methylene blue / phenyl salicylate)

Ask your doctor before using hyoscyamine together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking hyoscyamine. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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