Drug Interactions between fosphenytoin and itraconazole

Using itraconazole together with fosphenytoin may alter the blood levels and effects of both drugs. Using these medications together may cause itraconazole to be less effective. Contact your doctor immediately if your fungal infection worsens or if you experience twitching eye movements, slurred speech, loss of balance, tremor, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.