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Drug Interactions between foscarbidopa / foslevodopa and isoxsuprine

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

isoxsuprine foslevodopa

Applies to: isoxsuprine and foscarbidopa / foslevodopa

Consumer information for this interaction is not currently available.

MONITOR: The hypotensive and central nervous system (CNS) depressant effects of levodopa or foslevodopa may be additive with antihypertensive agents or agents with both hypotensive properties and CNS depressant effects. Postural hypotension may occur and/or the risk of sedation and impairment of attention, judgment, thinking, and psychomotor skills may increase.

MANAGEMENT: Hemodynamic responses should be monitored during coadministration, especially during the first few weeks of therapy. Dose adjustments of the concomitant agent may be required. Patients should be advised to notify their doctor if they experience dizziness or syncope and/or sudden, excessive or prolonged CNS effects that interfere with their normal activities. Patients should also be counseled to avoid hazardous activities requiring mental alertness and motor coordination until they know how these agents affect them.

Drug and food interactions

Moderate

foslevodopa food

Applies to: foscarbidopa / foslevodopa

Alcohol can increase the nervous system side effects of foslevodopa such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with foslevodopa. You may experience reduced effectiveness of foslevodopa in the presence of foods or enteral (tube) feedings with a high protein content. This may make the symptoms of Parkinson's disease worse. Talk with your doctor or nutrition counselor about the best foods to eat while you are taking this medication. Contact your doctor if your condition changes.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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