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Drug Interactions between Fluzone Preservative-Free and tazemetostat

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

influenza virus vaccine, inactivated tazemetostat

Applies to: Fluzone Preservative-Free (influenza virus vaccine, inactivated) and tazemetostat

If you are currently being treated or have recently been treated with tazemetostat, you should let your doctor know before receiving influenza virus vaccine, inactivated. Depending on the dose and length of time you have been on tazemetostat, you may have a reduced response to the vaccine. In some situations, your doctor may want to delay vaccination to give your body time to recover from the effects of tazemetostat therapy. If you have recently been vaccinated with influenza virus vaccine, inactivated, your doctor may choose to postpone treatment with tazemetostat for a couple of weeks or more. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Major

tazemetostat food

Applies to: tazemetostat

Do not consume grapefruit or grapefruit juice during treatment with tazemetostat. Grapefruit juice can significantly increase the blood levels and effects of tazemetostat, which may increase the risk of serious side effects such as bleeding complications, pain, bone pain, tiredness, shortness of breath, excess fluid around the lungs, and development of new (second) cancers. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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