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Drug Interactions between FemSeven Sequi Phase I and fitusiran

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

estradiol fitusiran

Applies to: FemSeven Sequi Phase I (estradiol) and fitusiran

Consumer information for this interaction is not currently available.

GENERALLY AVOID: Thrombotic events have been reported in fitusiran-treated patients, and concurrent use of hormonal contraceptives may increase the risk. Estrogen based hormonal contraceptives are an established risk factor for thrombosis in patients with inherited antithrombin (AT) deficiency.

MANAGEMENT: Concomitant use of fitusiran with estrogen based hormonal contraceptives should generally be avoided. Patients using hormonal contraceptives are advised to use alternative non-hormonal contraception prior to starting treatment with and while receiving fitusiran.

Drug and food interactions

Minor

estradiol food

Applies to: FemSeven Sequi Phase I (estradiol)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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