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Drug Interactions between Exjade and tovorafenib

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

deferasirox tovorafenib

Applies to: Exjade (deferasirox) and tovorafenib

Deferasirox may significantly increase the blood levels and effects of tovorafenib. This can increase the risk of side effects such as bleeding problems, skin reactions, including sensitivity to sunlight, liver problems, and slowed growth in children. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. Let your doctor know immediately if you develop side effects including coughing up blood or blood clots or red or black stools that look like tar, new or worsening skin reactions, or fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Drug and food interactions

Moderate

deferasirox food

Applies to: Exjade (deferasirox)

You may experience reduced absorption of deferasirox in the presence of food. Take deferasirox on an empty stomach 30 minutes before eating preferably at the same time everyday unless otherwise directed by your doctor. This will make it easier for your body to absorb the medication. The tablets should not be chewed or swallowed whole. The tablets should first be completely dispersed in water, orange juice, or apple juice, and the resulting suspension drunk immediately. After swallowing the suspension any residue should be resuspended in a small volume of the liquid and swallowed.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer