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Drug Interactions between esmolol and guanethidine / hydrochlorothiazide

This report displays the potential drug interactions for the following 2 drugs:

  • esmolol
  • guanethidine/hydrochlorothiazide

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Interactions between your drugs

Moderate

guanethidine esmolol

Applies to: guanethidine / hydrochlorothiazide and esmolol

Guanethidine may increase the effects of esmolol on your blood pressure and heart rate. Contact your doctor if you experience dizziness, lightheadedness, fainting, a slow pulse or heart rate, chest pain, shortness of breath, difficulty breathing, and/or swelling of the legs, ankles, or feet. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

guanethidine hydroCHLOROthiazide

Applies to: guanethidine / hydrochlorothiazide and guanethidine / hydrochlorothiazide

Before taking hydroCHLOROthiazide, tell your doctor if you also use guanethidine. You may need dose adjustments or special tests in order to safely take both medications together. The blood pressure lowering effects of this combination may be additive. You should take guanethidine at bedtime and to notify your doctor if have dizziness or feel faint. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor first.

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Drug and food interactions

No interactions were found. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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