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Drug Interactions between epinephrine and Rapiblyk

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

EPINEPHrine landiolol

Applies to: epinephrine and Rapiblyk (landiolol)

Consumer information for this interaction is not currently available.

MONITOR CLOSELY: Concomitant use of landiolol and epinephrine may attenuate the response to epinephrine in the treatment of anaphylactic reactions. Some authorities suggest sensitivity and severity of allergic reactions, towards allergens, may be increased in patients taking beta-blockers alone and landiolol may reduce the response to usual doses of epinephrine. Additionally, epinephrine may reduce the therapeutic effects of landiolol. Coadministration with positive inotropes, vasoconstrictors, or sympathomimetic agents (e.g., epinephrine) may decrease landiolol's heart rate and blood pressure lowering effects.

MANAGEMENT : If coadministration is clinically necessary, careful titration of the landiolol infusion, dose adjustment of either agent to achieve the desired effect, and close hemodynamic monitoring are advised. Consultation with package labeling and relevant institutional protocols may be advisable for further guidance.

Drug and food interactions

Moderate

EPINEPHrine food

Applies to: epinephrine

Both EPINEPHrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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