Drug Interactions between entrectinib and resmetirom
This report displays the potential drug interactions for the following 2 drugs:
- entrectinib
- resmetirom
Interactions between your drugs
entrectinib resmetirom
Applies to: entrectinib and resmetirom
Entrectinib may increase the blood levels and effects of resmetirom. This may increase the risk and or severity of side effects such as liver and/or gallbladder problems, diarrhea, nausea, itching, vomiting, constipation, abdominal pain, and dizziness. Seek immediate medical attention if you develop signs and symptoms of liver damage such as fever, chills, unusual bleeding or bruising, skin rash, fatigue, nausea, vomiting, dark colored urine, light colored stools, yellowing of the skin or eyes and pain or tenderness in the upper middle or upper right area of your stomach. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Talk to your doctor if you have any questions or are experiencing particularly bothersome side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
entrectinib food
Applies to: entrectinib
Do not consume grapefruit, grapefruit juice, or Seville oranges during treatment with entrectinib. Doing so can significantly increase the blood levels of entrectinib and increase the risk and/or severity of side effects such as dizziness; confusion; hallucinations; problems with concentration, attention, thinking, and memory; mood changes; insomnia; drowsiness; liver problems; increased uric acid levels in the blood (hyperuricemia); congestive heart failure; fluid retention and swelling; changes in electrical activity of the heart (a condition known as QT prolongation, which may lead to irregular heart rhythm that can be life-threatening); vision problems; and low red or white blood cell counts. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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