Drug Interactions between emtricitabine / rilpivirine / tenofovir alafenamide and Videx EC
This report displays the potential drug interactions for the following 2 drugs:
- emtricitabine/rilpivirine/tenofovir alafenamide
- Videx EC (didanosine)
Interactions between your drugs
didanosine tenofovir
Applies to: Videx EC (didanosine) and emtricitabine / rilpivirine / tenofovir alafenamide
Talk to your doctor before using didanosine together with tenofovir. Combining these medications may increase the blood levels and effects of didanosine. This can increase the risk of serious side effects such as pancreatitis (inflammation of the pancreas), lactic acidosis (the buildup of lactic acid in the body), and peripheral neuropathy (nerve damage, particularly in the hands and feet). You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience nausea, vomiting, abdominal pain, fatigue, weight loss, loss of appetite, shortness of breath, muscle weakness, or numbness, tingling, or pain in the hands and feet. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
didanosine food
Applies to: Videx EC (didanosine)
Food decreases the levels of didanosine in your body. Take didanosine on an empty stomach at least 30 minutes before or 2 hours after a meal. This will make it easier for your body to absorb the medication. Do not crush, chew, break, or open a delayed-release capsule (Videx EC). Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time.
rilpivirine food
Applies to: emtricitabine / rilpivirine / tenofovir alafenamide
Food significantly increases the absorption of rilpivirine. You should take each dose of rilpivirine with a meal. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication. Grapefruit juice can also increase the absorption of rilpivirine and should preferably be avoided.
tenofovir food
Applies to: emtricitabine / rilpivirine / tenofovir alafenamide
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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