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Drug Interactions between Duralutin and Rifadin IV

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

rifAMPin HYDROXYprogesterone

Applies to: Rifadin IV (rifampin) and Duralutin (hydroxyprogesterone)

RifAMPin may reduce the blood levels and effects of HYDROXYprogesterone. If you are using HYDROXYprogesterone for birth control, you may be at increased risk for pregnancy or breakthrough bleeding. You should discuss the use of alternative or additional methods of birth control with your healthcare provider. If you take HYDROXYprogesterone for another purpose, such as hormone replacement for menopause, notify your doctor if your medication is no longer controlling your symptoms or you experience abnormal bleeding. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

rifAMPin food

Applies to: Rifadin IV (rifampin)

Food can decrease the levels of rifAMPin in your body. Taking rifAMPin on an empty stomach (at least 30 minutes before or 2 hours after a meal) will make it easier for your body to absorb the medication. Avoid drinking alcohol while taking rifAMPin because alcohol use may increase the risk of damage to your liver. It is important to seek immediate medical care if you experience any severe side effects or symptoms of liver damage such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

HYDROXYprogesterone food

Applies to: Duralutin (hydroxyprogesterone)

Grapefruit juice may increase the blood levels of certain medications such as HYDROXYprogesterone. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with HYDROXYprogesterone. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

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Moderate

HYDROXYprogesterone food

Applies to: Duralutin (hydroxyprogesterone)

HYDROXYprogesterone may reduce the blood levels and effects of caffeine. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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