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Drug Interactions between doxazosin and propranolol

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

propranolol doxazosin

Applies to: propranolol and doxazosin

Using doxazosin and propranolol together can have increased effects on your blood pressure. You may be more likely to experience side effects such as dizziness, weakness, headache, flushing, fainting, and irregular heartbeat, especially if you have been on propranolol and are starting treatment with doxazosin. These effects may also occur following a dose increase of doxazosin or when doxazosin is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. You may need a dose adjustment or more frequent monitoring of your blood pressure to safely use both medications. Taking the doxazosin dose just before going to bed may help. Avoid driving or operating hazardous machinery until you know how these medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

propranolol food

Applies to: propranolol

Food can enhance the levels of propranolol in your body. You shoud take propranolol at the same time each day, preferably with or immediately following meals. This will make it easier for your body to absorb the medication. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking propranolol. Propranolol is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

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Moderate

doxazosin food

Applies to: doxazosin

Ask your doctor before using doxazosin together with ethanol (alcohol). Using doxazosin with ethanol (alcohol) can lower your blood pressure. This can cause dizziness or feeling like you might pass out, especially when getting up from a sitting or lying position. This may be more likely to occur when you first start taking either of these medications. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. You may develop flushing, warmth or redness under your skin or tingly feeling after alcohol intake (especially in you are of Asian descent) and should be advised to avoid alcohol or limit your intake. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

propranolol food

Applies to: propranolol

Using propranolol together with multivitamin with minerals may decrease the effects of propranolol. Separate the administration times of propranolol and multivitamin with minerals by at least 2 hours. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.