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Drug Interactions between dolutegravir and etravirine

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

etravirine dolutegravir

Applies to: etravirine and dolutegravir

Etravirine may reduce the blood levels of dolutegravir, which may make the medication less effective in treating HIV infection. You should not be taking these medications together unless you are also receiving either atazanavir/ritonavir, darunavir/ritonavir or lopinavir/ritonavir in your HIV regimen, since adding these agents helps to diminish the interaction between etravirine and dolutegravir. Contact a healthcare professional if you have any questions or concerns, and seek immediate medical attention if your condition worsens or you develop new infections during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

etravirine food

Applies to: etravirine

Etravirine should always be administered following a meal. Food enhances the levels of etravirine in your body. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

dolutegravir food

Applies to: dolutegravir

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer