Drug interactions between dolutegravir and etravirine
Interactions between your drugs
etravirine ↔ dolutegravir
Applies to:etravirine and dolutegravir
Etravirine may reduce the blood levels of dolutegravir, which may make the medication less effective in treating HIV infection. You should not be taking these medications together unless you are also receiving either atazanavir/ritonavir, darunavir/ritonavir or lopinavir/ritonavir in your HIV regimen, since adding these agents helps to diminish the interaction between etravirine and dolutegravir. Contact a healthcare professional if you have any questions or concerns, and seek immediate medical attention if your condition worsens or you develop new infections during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
Applies to: etravirine
Etravirine should always be administered following a meal. Food enhances the levels of etravirine in your body. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Applies to: dolutegravir
Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
For clinical details see professional interaction data.
Therapeutic duplication warnings
No therapeutic duplications were found for your selected drugs.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.