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Drug Interactions between diphtheria toxoid / hepatitis b pediatric vaccine / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid and procarbazine

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

procarbazine poliovirus vaccine, inactivated

Applies to: procarbazine and diphtheria toxoid / hepatitis b pediatric vaccine / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid

If you are currently being treated or have recently been treated with procarbazine, you should let your doctor know before receiving poliovirus vaccine, inactivated. Depending on the dose and length of time you have been on procarbazine, you may have a reduced response to the vaccine. In some situations, your doctor may want to delay vaccination to give your body time to recover from the effects of procarbazine therapy. If you have recently been vaccinated with poliovirus vaccine, inactivated, your doctor may choose to postpone treatment with procarbazine for a couple of weeks or more. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

procarbazine tetanus toxoid

Applies to: procarbazine and diphtheria toxoid / hepatitis b pediatric vaccine / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid

If you are currently being treated or have recently been treated with procarbazine, you should let your doctor know before receiving tetanus toxoid. Depending on the dose and length of time you have been on procarbazine, you may have a reduced response to the vaccine. In some situations, your doctor may want to delay vaccination to give your body time to recover from the effects of procarbazine therapy. If you have recently been vaccinated with tetanus toxoid, your doctor may choose to postpone treatment with procarbazine for a couple of weeks or more. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

procarbazine diphtheria toxoid

Applies to: procarbazine and diphtheria toxoid / hepatitis b pediatric vaccine / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid

If you are currently being treated or have recently been treated with procarbazine, you should let your doctor know before receiving diphtheria toxoid. Depending on the dose and length of time you have been on procarbazine, you may have a reduced response to the vaccine. In some situations, your doctor may want to delay vaccination to give your body time to recover from the effects of procarbazine therapy. If you have recently been vaccinated with diphtheria toxoid, your doctor may choose to postpone treatment with procarbazine for a couple of weeks or more. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

procarbazine pertussis, acellular

Applies to: procarbazine and diphtheria toxoid / hepatitis b pediatric vaccine / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid

If you are currently being treated or have recently been treated with procarbazine, you should let your doctor know before receiving pertussis, acellular. Depending on the dose and length of time you have been on procarbazine, you may have a reduced response to the vaccine. In some situations, your doctor may want to delay vaccination to give your body time to recover from the effects of procarbazine therapy. If you have recently been vaccinated with pertussis, acellular, your doctor may choose to postpone treatment with procarbazine for a couple of weeks or more. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

procarbazine hepatitis B pediatric vaccine

Applies to: procarbazine and diphtheria toxoid / hepatitis b pediatric vaccine / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid

If you are currently being treated or have recently been treated with procarbazine, you should let your doctor know before receiving hepatitis B pediatric vaccine. Depending on the dose and length of time you have been on procarbazine, you may have a reduced response to the vaccine. In some situations, your doctor may want to delay vaccination to give your body time to recover from the effects of procarbazine therapy. If you have recently been vaccinated with hepatitis B pediatric vaccine, your doctor may choose to postpone treatment with procarbazine for a couple of weeks or more. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Drug and food interactions

Major

procarbazine food

Applies to: procarbazine

During and within two weeks after treatment with procarbazine, you must not consume any foods or beverages that are high in tyramine content. Doing so can raise your blood pressure to dangerous levels, a condition known as hypertensive crisis. The condition is potentially fatal and may cause symptoms such as severe headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, convulsions, and sudden numbness or weakness (especially on one side of the body). You should seek immediate medical attention if you have any of these symptoms. Foods that are high in tyramine include, but are not limited to, air dried meats; aged or fermented meats; sausage or salami; pickled herring; anchovies; liver; red wine; beer; aged cheeses, including blue, brick, brie, cheddar, parmesan, romano, and swiss; sour cream; sauerkraut; canned figs; raisins; bananas or avocados (particularly if overripe); soy beans; soy sauce; tofu; miso soup; bean curd; fava beans; or yeast extracts (such as Marmite). You should avoid the use of alcohol while being treated with procarbazine, as alcohol may increase some of the nervous system side effects such as dizziness, drowsiness, and difficulty concentrating. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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