Drug Interactions between Diltiazem Hydrochloride SR and sodium nitrite
This report displays the potential drug interactions for the following 2 drugs:
- Diltiazem Hydrochloride SR (diltiazem)
- sodium nitrite
Interactions between your drugs
dilTIAZem sodium nitrite
Applies to: Diltiazem Hydrochloride SR (diltiazem) and sodium nitrite
When use of sodium nitrite is required, the doctor should be told if you have been receiving treatment with dilTIAZem. Sodium nitrite can cause hypotension (low blood pressure), and the risk may be greater when combined with other medications that decrease blood pressure such as dilTIAZem. Excessively low blood pressure can lead to shock, collapse, coma, or even death. Your doctor will need to monitor you closely and possibly take extra precautions for you to safely use these medications together. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
Applies to: Diltiazem Hydrochloride SR (diltiazem)
Alcohol can lower your blood pressure and add to the effects of dilTIAZem. You may experience dizziness, lightheadedness, fainting, or a rapid heartbeat if you drink alcohol with dilTIAZem, especially when you first start taking the medication or just after a dose increase. Grapefruit juice may also increase the effects of dilTIAZem in some people by increasing its levels in the blood. You may want to limit alcohol intake and avoid excessive consumption of grapefruit and grapefruit juice during treatment with dilTIAZem. However, if you have been regularly consuming grapefruit or grapefruit juice with dilTIAZem, do not alter the amounts of these products in your diet without first talking to your doctor or other healthcare professional. Contact your doctor if your condition changes or you experience increased side effects of dilTIAZem such as headache, irregular heartbeat, swelling, unexplained weight gain, or chest pain. Orange juice is not expected to interact.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.