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Drug interactions between digoxin and licorice

Results for the following 2 drugs:

Interactions between your drugs


digoxin licorice

Applies to: digoxin and licorice

Talk to your doctor before using licorice together with digoxin. Products containing licorice (glycyrrhizic acid) can cause high blood pressure as well as salt and water retention, which may interfere with the beneficial effects of digoxin. Regular use of licorice may also cause loss of magnesium and potassium, increasing the risk that you may experience toxic effects of digoxin. Generally, you should avoid or limit the consumption of licorice if you have high blood pressure, heart failure, pulmonary hypertension (high blood pressure in the vessels of the lung), or kidney disease. Check your food and medicine labels to be sure those products do not contain licorice or glycyrrhizic acid, which may be found in licorice-flavored chewing gum or candy, chewing tobacco, certain ethnic foods and beverages, and some herbal diuretics or laxatives. Contact your doctor if you experience potential toxic effects of digoxin such as nausea, vomiting, diarrhea, loss of appetite, visual disturbances (blurred vision; light halos around objects; green or yellow vision), or an abnormally fast or slow or uneven heartbeat. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Drug and food interactions


digoxin food

Applies to: digoxin

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

For clinical details see professional interaction data.

Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.