Drug Interactions between digitoxin and Fosamax Plus D
This report displays the potential drug interactions for the following 2 drugs:
- digitoxin
- Fosamax Plus D (alendronate/cholecalciferol)
Interactions between your drugs
digitoxin cholecalciferol
Applies to: digitoxin and Fosamax Plus D (alendronate / cholecalciferol)
Cholecalciferol can increase the levels of calcium in your body. Since calcium can enhance the effects of digitoxin on the heart, using too much cholecalciferol can cause digitoxin toxicity and irregular heart rhythm. If your doctor prescribes these medications together, you may need a dose adjustment or more frequent blood tests to monitor calcium and digitoxin levels. You should use cholecalciferol exactly as directed and avoid large increases in your daily dietary calcium intake while using cholecalciferol. Contact your doctor if you experience symptoms that could indicate high blood calcium, such as weakness, fatigue, headache, drowsiness, dizziness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, a metallic taste in the mouth, bone or muscle pain, incoordination, frequent urination, and weight loss. You should also seek medical attention if you experience symptoms of digitoxin toxicity such as nausea, vomiting, blurred vision, slow pulse, or irregular heartbeats. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
alendronate food
Applies to: Fosamax Plus D (alendronate / cholecalciferol)
Food may reduce the absorption of alendronate, which may lead to lower blood levels of the medication and possibly reduced effectiveness. You should take alendronate first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medication. Take each dose with a full glass (6 to 8 ounces) of water, and use only plain water (not mineral or vitamin water). Do not take alendronate if you cannot sit upright or stand for at least 30 minutes. Because alendronate can cause irritation and ulcer in the stomach or esophagus (the tube that connects your mouth and stomach), you will need to stay upright for at least 30 minutes after taking this medication. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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