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Drug Interactions between didanosine and Triumeq PD

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

didanosine dolutegravir

Applies to: didanosine and Triumeq PD (abacavir / dolutegravir / lamivudine)

The following interaction applies only if you are taking didanosine (Videx) buffered tablet or oral solution and not other didanosine formulations:

Taking the dolutegravir and didanosine doses too close together may interfere with the absorption of dolutegravir and reduce its effectiveness in treating HIV infection. To prevent or minimize the interaction, dolutegravir should be taken at least two hours before or six hours after the didanosine dose. Contact your doctor if your condition worsens or you develop new infections during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Drug and food interactions

Moderate

didanosine food

Applies to: didanosine

Food decreases the levels of didanosine in your body. Take didanosine on an empty stomach at least 30 minutes before or 2 hours after a meal. This will make it easier for your body to absorb the medication. Do not crush, chew, break, or open a delayed-release capsule (Videx EC). Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time.

Minor

dolutegravir food

Applies to: Triumeq PD (abacavir / dolutegravir / lamivudine)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer