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Drug Interactions between desipramine and Photofrin

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

desipramine porfimer

Applies to: desipramine and Photofrin (porfimer)

Using porfimer together with desipramine may increase the risk of a photosensitivity reaction (e.G., redness, swelling, itching, burning sensation, feeling hot, and/or blisters), following exposure to sunlight or bright indoor lights such as examination, dental or operating room lamps; floodlights; halogen lights; and unshaded light bulbs at close proximity. It is recommended that desipramine be avoided for at least 30 days following therapy with porfimer, and until a test for residual photosensitivity shows no photosensitivity reaction within 24 hours. In some cases, it might be necessary to avoid photosensitizing medications for 90 days or longer, although it may not be feasible to interrupt some treatments for that long, especially if they are medically necessary. Exposing your skin to normal indoor lighting is helpful as it will help your body get rid of porfimer more quickly, so you do not need to stay inside in the dark. Check with your doctor to see if you should temporarily withhold any of your medications after taking porfimer or if you have any other questions. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

desipramine food

Applies to: desipramine

Ask your doctor before using desipramine together with ethanol, this can alter the effects of desipramine and cause increased side effects. Call the doctor if you experience uneven heartbeats, extreme drowsiness, confusion, agitation, vomiting, blurred vision, sweating, muscle stiffness, feeling light-headed, and seizures. You should be warned not to exceed recommended dosages, to avoid alcohol, and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer