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Drug Interactions between dehydroepiandrosterone and fezolinetant

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

dehydroepiandrosterone (prasterone) fezolinetant

Applies to: dehydroepiandrosterone and fezolinetant

Consumer information for this interaction is not currently available.

GENERALLY AVOID: The concurrent use of fezolinetant with systemic estrogen hormone replacement therapy has not been evaluated in prospective clinical trials. Safety and efficacy of this combination are unknown. However, the concomitant use of vaginal estrogen preparations was excluded from this warning in the product labeling for Australia and the United Kingdom.

MANAGEMENT: Due to the lack of clinical data, use of fezolinetant with systemic estrogen-containing hormone replacement therapy is not recommended. Vaginal estrogen preparations may be used according to some authorities.

Drug and food interactions

Major

fezolinetant food

Applies to: fezolinetant

Consuming food or beverages that contain caffeine (e.G., chocolate, coffee, cola drinks, energy drinks, tea) is not recommended while taking fezolinetant. Caffeine may significantly increase the levels of fezolinetant in the blood. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer