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Drug interactions between Coreg and Respa-AR

Results for the following 2 drugs:
Coreg (carvedilol)
Respa-AR (atropine/chlorpheniramine/hyoscyamine/pseudoephedrine/scopolamine)

Interactions between your drugs

Moderate

hyoscyamine ↔ carvedilol

Applies to:Respa-AR (atropine/chlorpheniramine/hyoscyamine/pseudoephedrine/scopolamine) and Coreg (carvedilol)

Using hyoscyamine together with carvedilol may alter the effects of both medications. Contact your doctor if you experience drowsiness, dizziness, lightheadedness, confusion, blurred vision, dry mouth, or difficulty urinating. You may need a dose adjustment or need your blood pressure checked more often to safely use both medications. You should avoid activities requiring mental alertness until you know how the medications will affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Moderate

pseudoephedrine ↔ carvedilol

Applies to:Respa-AR (atropine/chlorpheniramine/hyoscyamine/pseudoephedrine/scopolamine) and Coreg (carvedilol)

Consumer information for this interaction is not currently available.

MONITOR: Sympathomimetic agents, such as pseudoephedrine, may antagonize the effects of antihypertensives that interfere with sympathetic activity, such as alpha- and beta-adrenergic blocking agents. In contrast, alpha- and beta-blockers may diminish the vasoconstrictive effects of sympathomimetics. The mechanism of this interaction has not been reported, but may involve competitive inhibition at the adrenergic receptor. Severe hypertension may occur in patients receiving beta-blockers.

MANAGEMENT: Caution and close monitoring of blood pressure is recommended if pseudoephedrine is administered with these antihypertensives. Discontinuation of the sympathomimetic may be necessary if hypertension develops.

References

  1. Cerner Multum, Inc. "Australian Product Information." O 0
  2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  3. "Product Information. Allegra-D (fexofenadine-pseudoephedrine)." Hoechst Marion-Roussel Inc, Kansas City, MO.
Moderate

atropine ↔ carvedilol

Applies to:Respa-AR (atropine/chlorpheniramine/hyoscyamine/pseudoephedrine/scopolamine) and Coreg (carvedilol)

Using atropine together with carvedilol may alter the effects of both medications. Contact your doctor if you experience drowsiness, dizziness, lightheadedness, confusion, blurred vision, dry mouth, or difficulty urinating. You may need a dose adjustment or need your blood pressure checked more often to safely use both medications. You should avoid activities requiring mental alertness until you know how the medications will affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Moderate

scopolamine ↔ carvedilol

Applies to:Respa-AR (atropine/chlorpheniramine/hyoscyamine/pseudoephedrine/scopolamine) and Coreg (carvedilol)

Using scopolamine together with carvedilol may alter the effects of both medications. Contact your doctor if you experience drowsiness, dizziness, lightheadedness, confusion, blurred vision, dry mouth, or difficulty urinating. You may need a dose adjustment or need your blood pressure checked more often to safely use both medications. You should avoid activities requiring mental alertness until you know how the medications will affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Drug and food interactions

Moderate

chlorpheniramine food

Applies to: Respa-AR (atropine / chlorpheniramine / hyoscyamine / pseudoephedrine / scopolamine)

Alcohol can increase the nervous system side effects of chlorpheniramine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with chlorpheniramine. Do not use more than the recommended dose of chlorpheniramine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

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Minor

scopolamine food

Applies to: Respa-AR (atropine / chlorpheniramine / hyoscyamine / pseudoephedrine / scopolamine)

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

For clinical details see professional interaction data.

Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Disclaimer: Every effort has been made to ensure that the information provided by Multum is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. Multum's information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill, knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2018 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.

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