Drug Interactions between conjugated estrogens / medroxyprogesterone and elafibranor

Elafibranor may reduce the blood levels and effectiveness of medroxyPROGESTERone, which may make it less reliable as a form of birth control. This is particularly important because elafibranor may cause fetal harm. Alternative or additional methods of birth control such as condoms should be used during treatment with elafibranor and for 3 weeks after stopping treatment to avoid unintended pregnancy. Talk to your gynecologist or other healthcare professional for help in selecting an effective method of birth control that is best for you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Elafibranor may reduce the blood levels and effects of conjugated estrogens. If you are using low-dose oral contraceptives, you may have an increased risk of breakthrough bleeding and unintended pregnancy. You should discuss the use of alternative or additional methods of birth control with your healthcare provider. If you take hormone replacement for menopause, notify your doctor if your medication is no longer controlling your symptoms or you experience abnormal bleeding. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.