Drug Interactions between Combivir and Decadron with Xylocaine
This report displays the potential drug interactions for the following 2 drugs:
- Combivir (lamivudine/zidovudine)
- Decadron with Xylocaine (dexamethasone/lidocaine)
Interactions between your drugs
zidovudine dexAMETHasone
Applies to: Combivir (lamivudine / zidovudine) and Decadron with Xylocaine (dexamethasone / lidocaine)
Using zidovudine together with dexAMETHasone may increase the risk of muscle disorders, including a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue. In some cases, rhabdomyolysis can cause kidney damage and even death. Call your doctor immediately if you have unexplained muscle pain, tenderness, or weakness while taking the medications, especially if these symptoms are accompanied by fever or dark colored urine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
lidocaine dexAMETHasone
Applies to: Decadron with Xylocaine (dexamethasone / lidocaine) and Decadron with Xylocaine (dexamethasone / lidocaine)
Information for this minor interaction is available on the professional version.
Drug and food interactions
lidocaine food
Applies to: Decadron with Xylocaine (dexamethasone / lidocaine)
Grapefruit juice may increase the blood levels of lidocaine, which may increase the risk of side effects such as low blood pressure, slow heart rate, irregular heart rhythm, difficulty breathing and convulsions. Cigarette smoking may reduce the blood levels of lidocaine, which may make the medication less effective. It is best to avoid smoking during lidocaine therapy. Consuming cruciferous vegetables (e.G., broccoli, brussels sprouts) may also reduce the blood levels of lidocaine. Talk to a healthcare professional if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
zidovudine food
Applies to: Combivir (lamivudine / zidovudine)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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