Drug Interactions between choline salicylate / magnesium salicylate and grepafloxacin

Using choline salicylate together with magnesium salicylate is generally not recommended. Combining these medications may increase the risk of side effects in the gastrointestinal tract such as inflammation, pain, bleeding, and ulceration. Bruising and other bleeding complications may also occur. You should take these medications with food to lessen gastrointestinal side effects. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. You should seek immediate medical attention if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Grepafloxacin may rarely cause central nervous system side effects such as tremors, involuntary muscle movements, anxiety, confusion, depression, hallucinations or seizures, and combining it with other medications that can also affect the central nervous system such as choline salicylate may increase that risk. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Grepafloxacin and magnesium salicylate should not be taken orally at the same time. Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of grepafloxacin into the bloodstream and reduce its effectiveness. If possible, it may be best to avoid taking magnesium salicylate while you are being treated with grepafloxacin. Otherwise, grepafloxacin should be taken 2 to 4 hours before or 4 to 6 hours after a magnesium salicylate dose, grepafloxacin should be taken at least 2 hours before and not less than 6 hours after Suprep Bowel Prep (magnesium/potassium/sodium sulfates), or grepafloxacin and magnesium salicylate should be taken as directed by your healthcare provider. Talk to your healthcare provider if you are unsure whether your medications contain something that could potentially interact or if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.