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Drug Interactions between cholestyramine and Simliya

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

cholestyramine ethinyl estradiol

Applies to: cholestyramine and Simliya (desogestrel / ethinyl estradiol)

Cholestyramine may interfere with the absorption of ethinyl estradiol when these medications are taken at the same time. This may reduce the blood levels and effects of ethinyl estradiol. To prevent or minimize the interaction, ethinyl estradiol should be taken at least 1 hour before or 4 to 6 hours after the cholestyramine dose. Contact your doctor if your condition changes or your symptoms worsen during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

cholestyramine desogestrel

Applies to: cholestyramine and Simliya (desogestrel / ethinyl estradiol)

Cholestyramine may interfere with the absorption of desogestrel when these medications are taken at the same time. This may reduce the blood levels and effects of desogestrel. To prevent or minimize the interaction, desogestrel should be taken at least 1 hour before or 4 to 6 hours after the cholestyramine dose. Contact your doctor if your condition changes or your symptoms worsen during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

desogestrel food

Applies to: Simliya (desogestrel / ethinyl estradiol)

Grapefruit juice may increase the blood levels of certain medications such as desogestrel. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with desogestrel. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

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Moderate

cholestyramine food

Applies to: cholestyramine

Using cholestyramine together with multivitamin with minerals may decrease the effects of multivitamin with minerals. Multivitamin with minerals should be administered at least 4 hours before cholestyramine. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

ethinyl estradiol food

Applies to: Simliya (desogestrel / ethinyl estradiol)

Information for this minor interaction is available on the professional version.

Minor

ethinyl estradiol food

Applies to: Simliya (desogestrel / ethinyl estradiol)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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