Can you take Chlorotrianisene with Conestat alfa?
1 drug interaction and 3 additional warnings found for the following 2 drugs:
- chlorotrianisene
- conestat alfa
Drug interactions
Moderate drug interactions
Moderate:
chlorotrianisene conestat alfa
Applies to: chlorotrianisene and conestat alfa
Conestat alfa can occasionally cause dangerous blood clots, and using it together with chlorotrianisene may increase the risk. Also, the risk is increased with age, cigarette smoking, high blood pressure, or high cholesterol. Blood clots can lead to complications such as heart attack, pulmonary embolism (blockage of an artery in the lung), and stroke. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. You should seek immediate medical attention if you experience potential signs and symptoms of blood clots such as chest pain; shortness of breath; difficulty breathing; coughing up blood; sudden loss of vision; pain, redness or swelling in an arm or leg; and numbness or weakness on one side of the body. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Food/lifestyle interactions
Minor food/lifestyle interactions
Minor:
chlorotrianisene Food/Lifestyle
Applies to: chlorotrianisene
Information for this minor interaction is available on the professional version.
Disease interactions
2 potential interactions Applies to: 2 conditions, including Thrombotic/Thromboembolic Disorder and History, Thrombotic/Thromboembolic Disorder.
History, Thrombotic/Thromboembolic Disorder
Moderate:
conestat alfa
Conestat alfa has a moderate potential interaction with History, Thrombotic/Thromboembolic Disorder.
Serious arterial and venous thromboembolic (TE) events have been reported at the recommended dose of plasma derived conestat alfa. Patients with risk factors such as, prior history of thrombosis might be at an increased risk. It is recommended to monitor patients with known risk factors for TE events during and after therapy administration.
Thrombotic/Thromboembolic Disorder
Moderate:
conestat alfa
Conestat alfa has a moderate potential interaction with Thrombotic/Thromboembolic Disorder.
Serious arterial and venous thromboembolic (TE) events have been reported at the recommended dose of plasma derived conestat alfa. Patients with risk factors such as, prior history of thrombosis might be at an increased risk. It is recommended to monitor patients with known risk factors for TE events during and after therapy administration.
More resources
chlorotrianisene
A total of 260 drugs are known to interact with chlorotrianisene.
- Chlorotrianisene is in the drug class estrogens.
- Chlorotrianisene is used to treat Postmenopausal Symptoms.
conestat alfa
A total of 66 drugs are known to interact with conestat alfa.
- Conestat alfa is in the drug class hereditary angioedema agents.
- Conestat alfa is used to treat Hereditary Angioedema.
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.