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Drug Interactions between cemiplimab and Vaxelis

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

poliovirus vaccine, inactivated cemiplimab

Applies to: Vaxelis (diphtheria toxoid / haemophilus b conjugate (prp-omp) vaccine / hepatitis b pediatric vaccine / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid) and cemiplimab

If you are currently being treated or are going to begin treatment with cemiplimab, you should let your doctor know before receiving poliovirus vaccine, inactivated. Cemiplimab can cause potentially serious immune-related side effects and receiving poliovirus vaccine, inactivated during treatment with cemiplimab may increase that risk. Your healthcare provider may already be aware of the risks but has determined that this is the best course of treatment for you and is monitoring you closely for any potential complications. You should seek immediate medical attention if you experience severe diarrhea; serious skin reactions such as a widespread rash, peeling skin, or blisters; signs of liver problems like yellowing of your skin or eyes, or pain on the right side of your abdomen; lung issues such as shortness of breath, chest pain, coughing, or extreme fatigue; kidney problems like difficulty urinating, sudden weight gain, or swelling in your feet, ankles, or legs; or thyroid and other endocrine issues such as fatigue, sluggishness, constipation, depression, hoarseness, or unexplained weight gain.

Moderate

tetanus toxoid cemiplimab

Applies to: Vaxelis (diphtheria toxoid / haemophilus b conjugate (prp-omp) vaccine / hepatitis b pediatric vaccine / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid) and cemiplimab

If you are currently being treated or are going to begin treatment with cemiplimab, you should let your doctor know before receiving tetanus toxoid. Cemiplimab can cause potentially serious immune-related side effects and receiving tetanus toxoid during treatment with cemiplimab may increase that risk. Your healthcare provider may already be aware of the risks but has determined that this is the best course of treatment for you and is monitoring you closely for any potential complications. You should seek immediate medical attention if you experience severe diarrhea; serious skin reactions such as a widespread rash, peeling skin, or blisters; signs of liver problems like yellowing of your skin or eyes, or pain on the right side of your abdomen; lung issues such as shortness of breath, chest pain, coughing, or extreme fatigue; kidney problems like difficulty urinating, sudden weight gain, or swelling in your feet, ankles, or legs; or thyroid and other endocrine issues such as fatigue, sluggishness, constipation, depression, hoarseness, or unexplained weight gain.

Moderate

diphtheria toxoid cemiplimab

Applies to: Vaxelis (diphtheria toxoid / haemophilus b conjugate (prp-omp) vaccine / hepatitis b pediatric vaccine / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid) and cemiplimab

If you are currently being treated or are going to begin treatment with cemiplimab, you should let your doctor know before receiving diphtheria toxoid. Cemiplimab can cause potentially serious immune-related side effects and receiving diphtheria toxoid during treatment with cemiplimab may increase that risk. Your healthcare provider may already be aware of the risks but has determined that this is the best course of treatment for you and is monitoring you closely for any potential complications. You should seek immediate medical attention if you experience severe diarrhea; serious skin reactions such as a widespread rash, peeling skin, or blisters; signs of liver problems like yellowing of your skin or eyes, or pain on the right side of your abdomen; lung issues such as shortness of breath, chest pain, coughing, or extreme fatigue; kidney problems like difficulty urinating, sudden weight gain, or swelling in your feet, ankles, or legs; or thyroid and other endocrine issues such as fatigue, sluggishness, constipation, depression, hoarseness, or unexplained weight gain.

Moderate

pertussis, acellular cemiplimab

Applies to: Vaxelis (diphtheria toxoid / haemophilus b conjugate (prp-omp) vaccine / hepatitis b pediatric vaccine / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid) and cemiplimab

If you are currently being treated or are going to begin treatment with cemiplimab, you should let your doctor know before receiving pertussis, acellular. Cemiplimab can cause potentially serious immune-related side effects and receiving pertussis, acellular during treatment with cemiplimab may increase that risk. Your healthcare provider may already be aware of the risks but has determined that this is the best course of treatment for you and is monitoring you closely for any potential complications. You should seek immediate medical attention if you experience severe diarrhea; serious skin reactions such as a widespread rash, peeling skin, or blisters; signs of liver problems like yellowing of your skin or eyes, or pain on the right side of your abdomen; lung issues such as shortness of breath, chest pain, coughing, or extreme fatigue; kidney problems like difficulty urinating, sudden weight gain, or swelling in your feet, ankles, or legs; or thyroid and other endocrine issues such as fatigue, sluggishness, constipation, depression, hoarseness, or unexplained weight gain.

Moderate

haemophilus b conjugate (PRP-OMP) vaccine cemiplimab

Applies to: Vaxelis (diphtheria toxoid / haemophilus b conjugate (prp-omp) vaccine / hepatitis b pediatric vaccine / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid) and cemiplimab

If you are currently being treated or are going to begin treatment with cemiplimab, you should let your doctor know before receiving haemophilus b conjugate (PRP-OMP) vaccine. Cemiplimab can cause potentially serious immune-related side effects and receiving haemophilus b conjugate (PRP-OMP) vaccine during treatment with cemiplimab may increase that risk. Your healthcare provider may already be aware of the risks but has determined that this is the best course of treatment for you and is monitoring you closely for any potential complications. You should seek immediate medical attention if you experience severe diarrhea; serious skin reactions such as a widespread rash, peeling skin, or blisters; signs of liver problems like yellowing of your skin or eyes, or pain on the right side of your abdomen; lung issues such as shortness of breath, chest pain, coughing, or extreme fatigue; kidney problems like difficulty urinating, sudden weight gain, or swelling in your feet, ankles, or legs; or thyroid and other endocrine issues such as fatigue, sluggishness, constipation, depression, hoarseness, or unexplained weight gain.

Moderate

hepatitis B pediatric vaccine cemiplimab

Applies to: Vaxelis (diphtheria toxoid / haemophilus b conjugate (prp-omp) vaccine / hepatitis b pediatric vaccine / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid) and cemiplimab

If you are currently being treated or are going to begin treatment with cemiplimab, you should let your doctor know before receiving hepatitis B pediatric vaccine. Cemiplimab can cause potentially serious immune-related side effects and receiving hepatitis B pediatric vaccine during treatment with cemiplimab may increase that risk. Your healthcare provider may already be aware of the risks but has determined that this is the best course of treatment for you and is monitoring you closely for any potential complications. You should seek immediate medical attention if you experience severe diarrhea; serious skin reactions such as a widespread rash, peeling skin, or blisters; signs of liver problems like yellowing of your skin or eyes, or pain on the right side of your abdomen; lung issues such as shortness of breath, chest pain, coughing, or extreme fatigue; kidney problems like difficulty urinating, sudden weight gain, or swelling in your feet, ankles, or legs; or thyroid and other endocrine issues such as fatigue, sluggishness, constipation, depression, hoarseness, or unexplained weight gain.

Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.