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Drug Interactions between celecoxib / tramadol and digoxin

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

digoxin traMADol

Applies to: digoxin and celecoxib / tramadol

Before using digoxin, tell your doctor if you also use traMADol. This combination may cause nausea, loss of appetite, visual changes, slow pulse, or irregular heartbeats. If you take both medications together, tell your doctor if you have any of these symptoms. You may need a dose adjustment or special tests if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

digoxin celecoxib

Applies to: digoxin and celecoxib / tramadol

Before taking celecoxib, tell your doctor if you also use digoxin. You may need dose adjustments or special tests in order to safely take both medications together. This combination may increase digoxin levels. You should notify your doctor if you have symptoms of nausea, loss of appetite, visual changes, slow pulse, or irregular heartbeats. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

traMADol celecoxib

Applies to: celecoxib / tramadol and celecoxib / tramadol

Celecoxib may increase the blood levels and effects of traMADol. If your doctor does prescribe these medications together, you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience increased side effects or if your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Drug and food interactions

Moderate

traMADol food

Applies to: celecoxib / tramadol

Alcohol can increase the nervous system side effects of traMADol such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with traMADol. Do not use more than the recommended dose of traMADol, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

Minor

digoxin food

Applies to: digoxin

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer