Drug Interactions between caffeine / pheniramine / phenylephrine / sodium citrate / sodium salicylate and influenza virus vaccine, live

Vaccination with influenza virus vaccine, live is not recommended in children less than 18 years of age who are receiving sodium salicylate therapy. The use of sodium salicylate or related medications has been linked to a serious and potentially fatal condition called Reye's syndrome in children with certain viral infections such as influenza or chicken pox. Because influenza virus vaccine, live contains live (but weakened) virus, there is some concern that it can cause Reye's syndrome when used with sodium salicylate. The immunizing doctor should be informed of current or recent therapy with sodium salicylate so that appropriate measures and/or precautions can be taken, such as substituting influenza virus vaccine, live with a vaccine that contains inactivated virus. Never give sodium salicylate to children or adolescents who have a fever without talking to a doctor, especially if they also have flu symptoms or chicken pox. It is important to tell the doctor about all other medications being used, including vitamins and herbs. Do not stop using any medications without first talking to the doctor.

Both phenylephrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Using sodium citrate together with sodium salicylate may decrease the effects of sodium salicylate. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.