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Can you take Bulevirtide with Nubeqa?

1 drug interaction and 3 additional warnings found for the following 2 drugs:

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Drug interactions

Minor drug interactions

Minor:

darolutamide bulevirtide

Applies to: Nubeqa (darolutamide) and bulevirtide

Information for this minor interaction is available on the professional version.

Food/lifestyle interactions

Moderate food/lifestyle interactions

Moderate:

darolutamide Food/Lifestyle

Applies to: Nubeqa (darolutamide)

Food helps with the absorption of darolutamide into the blood stream.

You should take this medication with food as directed.

Disease interactions

2 potential interactions Applies to: 2 conditions, including Liver Disease and Renal Dysfunction.

Liver Disease

Moderate:

Nubeqa

The darolutamide in Nubeqa has a moderate potential interaction with Liver Disease.

Patients with moderate hepatic impairment (Child-Pugh Class B) have a higher exposure to darolutamide and reduction of the dose is recommended (see manufacturer package insert for recommended dose). No dose reduction is needed for patients with mild hepatic impairment. The effect of severe hepatic impairment (Child-Pugh C) on darolutamide pharmacokinetics is unknown.

Renal Dysfunction

Moderate:

Nubeqa

The darolutamide in Nubeqa has a moderate potential interaction with Renal Dysfunction.

Patients with severe renal impairment (eGFR 15-29 mL/min/1.73 m2) who are not receiving hemodialysis have a higher exposure to darolutamide and reduction of the dose is recommended (see manufacturer package insert for recommended dose). No dose reduction is needed for patients with mild or moderate renal impairment. The effect of end stage renal disease (eGFR <15 mL/min/1.73 m2) on darolutamide pharmacokinetics is unknown.

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More resources

bulevirtide

A total of 288 drugs are known to interact with bulevirtide.

Nubeqa

A total of 341 drugs are known to interact with Nubeqa.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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