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Drug Interactions between Breztri Aerosphere and metoprolol

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

metoprolol glycopyrrolate

Applies to: metoprolol and Breztri Aerosphere (budesonide / formoterol / glycopyrrolate)

Using glycopyrrolate together with metoprolol may alter the effects of both medications. Contact your doctor if you experience drowsiness, dizziness, lightheadedness, confusion, blurred vision, dry mouth, or difficulty urinating. You may need a dose adjustment or need your blood pressure checked more often to safely use both medications. You should avoid activities requiring mental alertness until you know how the medications will affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

metoprolol budesonide

Applies to: metoprolol and Breztri Aerosphere (budesonide / formoterol / glycopyrrolate)

Budesonide may reduce the effects of metoprolol in lowering blood pressure. The interaction is most likely to occur when budesonide is used for more than a week, since prolonged use can cause sodium and water retention. Let your doctor know if you experience sudden, unexplained weight gain or swelling of the hands, ankles, or feet. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

metoprolol formoterol

Applies to: metoprolol and Breztri Aerosphere (budesonide / formoterol / glycopyrrolate)

Using metoprolol together with formoterol may reduce the benefits of both medications, since they have opposing effects in the body. In addition, metoprolol can sometimes cause narrowing of the airways, which may worsen your breathing problems or trigger severe asthmatic attacks. You may not be able to use metoprolol if you have frequent asthma attacks or severe asthma or COPD (chronic obstructive pulmonary disease), or you may need a dose adjustment and more frequent monitoring of your lung function to safely use both medications. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. Let your doctor know if you experience wheezing, shortness of breath, chest tightness, or other breathing difficulties during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

budesonide formoterol

Applies to: Breztri Aerosphere (budesonide / formoterol / glycopyrrolate) and Breztri Aerosphere (budesonide / formoterol / glycopyrrolate)

Information for this minor interaction is available on the professional version.

Drug and food interactions

Moderate

metoprolol food

Applies to: metoprolol

Food can enhance the levels of metoprolol in your body. You should take metoprolol at the same time each day, preferably with or immediately following meals. This will make it easier for your body to absorb the medication. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking metoprolol. Metoprolol is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

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Moderate

budesonide food

Applies to: Breztri Aerosphere (budesonide / formoterol / glycopyrrolate)

You should avoid the regular consumption of large amounts of grapefruits and grapefruit juice while taking budesonide. Grapefruit can raise the levels of budesonide in your body and lead to increased side effects. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

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Moderate

glycopyrrolate food

Applies to: Breztri Aerosphere (budesonide / formoterol / glycopyrrolate)

Ask your doctor before using glycopyrrolate together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking glycopyrrolate. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

metoprolol food

Applies to: metoprolol

Using metoprolol together with multivitamin with minerals may decrease the effects of metoprolol. Separate the administration times of metoprolol and multivitamin with minerals by at least 2 hours. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.