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Drug interactions between bexarotene and gemfibrozil

Results for the following 2 drugs:
bexarotene
gemfibrozil

Interactions between your drugs

Major

gemfibrozil bexarotene

Applies to: gemfibrozil and bexarotene

Using bexarotene together with gemfibrozil is generally not recommended. Combining these medications may significantly increase the blood levels of bexarotene. You may be more likely to experience serious side effects such as elevated cholesterol and triglyceride levels, underactive thyroid (hypothyroidism), liver function abnormalities, low blood cell counts, and inflammation of the pancreas (pancreatitis). Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

bexarotene food

Applies to: bexarotene

Food helps with the absorption of bexarotene from the gastrointestinal tract into the blood stream. You should take each dose the same time everyday with a meal. Avoid consuming large amounts of grapefruit or grapefruit juice during treatment, since doing so may increase the blood levels of bexarotene. Talk to your doctor or pharmacist if you have any questions or concerns about your medication. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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