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Drug Interactions between Bactrim IV and MSP-Blu

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

methenamine sulfamethoxazole

Applies to: MSP-Blu (hyoscyamine / methenamine / methylene blue / phenyl salicylate) and Bactrim IV (sulfamethoxazole / trimethoprim)

Using methenamine together with sulfamethoxazole is not recommended. Combining these medications may cause crystals to form in the urine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

sulfamethoxazole food

Applies to: Bactrim IV (sulfamethoxazole / trimethoprim)

Ask your doctor before using sulfamethoxazole together with ethanol. Contact your doctor if you experience unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, or vomiting. If you experience these side effects, you may need to avoid ethanol while taking sulfamethoxazole. You should check your food and medicine labels to see if these products contain ethanol. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

hyoscyamine food

Applies to: MSP-Blu (hyoscyamine / methenamine / methylene blue / phenyl salicylate)

Ask your doctor before using hyoscyamine together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking hyoscyamine. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Urinary anti-infectives

Therapeutic duplication

The recommended maximum number of medicines in the 'urinary anti-infectives' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'urinary anti-infectives' category:

  • Bactrim IV (sulfamethoxazole/trimethoprim)
  • MSP-Blu (hyoscyamine/methenamine/methylene blue/phenyl salicylate)

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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