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Drug interactions between B-Nexa and crizotinib

Results for the following 2 drugs:
B-Nexa (calcium/folic acid/ginger/pyridoxine)
crizotinib

Interactions between your drugs

Moderate

ginger crizotinib

Applies to: B-Nexa (calcium / folic acid / ginger / pyridoxine) and crizotinib

Ginger may increase the blood levels and side effects of crizotinib. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience fever, rash, abdominal pain, yellowing of the skin or the whites of your eyes, dark urine, fatigue, weakness, unusual bleeding or bruising, loss of appetite, nausea, or vomiting. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Major

crizotinib food

Applies to: crizotinib

Do not consume grapefruit or grapefruit juice during treatment with crizotinib unless directed otherwise by your doctor. Grapefruit juice can increase the blood levels of crizotinib to dangerous levels and cause an irregular heart rhythm that may be serious. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or fast or pounding heartbeats during treatment with crizotinib. You may take crizotinib with or without food, but take it the same time each day. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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