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Drug Interactions between avapritinib and VSL#3 Junior

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

lactobacillus acidophilus avapritinib

Applies to: VSL#3 Junior (bifidobacterium infantis / lactobacillus acidophilus / streptococcus thermophilus) and avapritinib

If you are currently being treated or have recently been treated with avapritinib, you should let your doctor know before using lactobacillus acidophilus. Depending on the dose and length of time you have been on avapritinib, you may be at risk for developing rare infections from exposure to products containing live bacteria or yeast. Depending on your overall health and medical condition, it may be advisable to avoid using lactobacillus acidophilus until your immune system has recovered from the effects of avapritinib. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

bifidobacterium infantis avapritinib

Applies to: VSL#3 Junior (bifidobacterium infantis / lactobacillus acidophilus / streptococcus thermophilus) and avapritinib

If you are currently being treated or have recently been treated with avapritinib, you should let your doctor know before using bifidobacterium infantis. Depending on the dose and length of time you have been on avapritinib, you may be at risk for developing rare infections from exposure to products containing live bacteria or yeast. Depending on your overall health and medical condition, it may be advisable to avoid using bifidobacterium infantis until your immune system has recovered from the effects of avapritinib. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

streptococcus thermophilus avapritinib

Applies to: VSL#3 Junior (bifidobacterium infantis / lactobacillus acidophilus / streptococcus thermophilus) and avapritinib

If you are currently being treated or have recently been treated with avapritinib, you should let your doctor know before using streptococcus thermophilus. Depending on the dose and length of time you have been on avapritinib, you may be at risk for developing rare infections from exposure to products containing live bacteria or yeast. Depending on your overall health and medical condition, it may be advisable to avoid using streptococcus thermophilus until your immune system has recovered from the effects of avapritinib. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Drug and food interactions

Major

avapritinib food

Applies to: avapritinib

Avapritinib should be taken on an empty stomach, one hour before or two hours after a meal. Do not consume grapefruit, grapefruit juice, or any supplements that contain grapefruit extract during treatment with avapritinib unless directed otherwise by your doctor. Grapefruit juice can increase the blood levels of avapritinib. This may increase the risk and/or severity of serious side effects such as bleeding in the brain; cognitive impairment (forgetfulness, confusion, trouble thinking); changes in mood or behavior; hallucinations; fluid retention or swelling; and decreases in blood cell counts. You may also be more likely to develop anemia, bleeding problems, or infections due to low blood cell counts. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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