Can you take Antioxidant Formula with Polygam S/D?
No drug interactions found, but 9 warnings to review for the following 2 drugs:
- Antioxidant Formula (multivitamin with minerals)
- Polygam S/D (immune globulin intravenous)
Drug interactions
There were no interactions found between Antioxidant Formula and Polygam S/D. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Food/lifestyle interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease interactions
9 potential interactions Applies to: 8 conditions, including Diabetes Mellitus, Hyponatremia, Cardiovascular Conditions and Disorders, Sepsis, and Renal Dysfunction.
Cardiovascular Conditions and Disorders
Major:
Polygam S/D
The immune globulin intravenous in Polygam S/D has a major potential interaction with Cardiovascular Conditions and Disorders.
Thrombosis has been reported after treatment with immune globulin products. In general, patients at greatest risk of thromboembolic events are those of advanced age, prolonged immobilization, hypercoagulable conditions, history of venous or arterial thrombosis, use of estrogens, indwelling central vascular catheters, hyperviscosity, and cardiovascular risk factors. Thrombosis may occur in the absence of known risk factors; therefore, it is recommended that patients treated with these agents should be monitored for signs and symptoms of thrombosis and assess blood viscosity in patients at risk. Consider baseline assessment of blood viscosity in patients at risk for hyperviscosity.
Diabetes Mellitus
Major:
Polygam S/D
The immune globulin intravenous in Polygam S/D has a major potential interaction with Diabetes Mellitus.
Thrombosis has been reported after treatment with immune globulin products. In general, patients at greatest risk of thromboembolic events are those of advanced age, prolonged immobilization, hypercoagulable conditions, history of venous or arterial thrombosis, use of estrogens, indwelling central vascular catheters, hyperviscosity, and cardiovascular risk factors. Thrombosis may occur in the absence of known risk factors; therefore, it is recommended that patients treated with these agents should be monitored for signs and symptoms of thrombosis and assess blood viscosity in patients at risk. Consider baseline assessment of blood viscosity in patients at risk for hyperviscosity.
Major:
Polygam S/D
The immune globulin intravenous in Polygam S/D has a major potential interaction with Diabetes Mellitus.
Renal abnormalities such as acute tubular necrosis, proximal tubular nephropathy, osmotic nephrosis, including acute renal dysfunction/failure and death have been reported after immune globulin intravenous (IGIV) products. Cases of renal dysfunction and acute renal failure occur more commonly in patients receiving IGIV products containing sucrose as a stabilizer. Ensure that patients are not volume-depleted before administering these agents and assess renal function, including measurement of blood urea nitrogen (BUN) and serum creatinine, before initiating the infusion and at appropriate intervals thereafter. If renal function deteriorates, consider discontinuation of the product. Periodic monitoring of renal function and urine output is important in patients at increased risk of developing acute renal failure. Administer these agents at the minimum dose and rate of infusion practicable in patients at risk for renal dysfunction or failure.
Fructose Intolerance
Major:
Polygam S/D
The immune globulin intravenous in Polygam S/D has a major potential interaction with Fructose Intolerance.
The immune globulin intravenous (human) injection, Flebogamma 10% DIF and Gammaplex contain sorbitol and should not be administered to patients with hereditary fructose intolerance (HFI).
History, Thrombotic/Thromboembolic Disorder
Major:
Polygam S/D
The immune globulin intravenous in Polygam S/D has a major potential interaction with History, Thrombotic/Thromboembolic Disorder.
Thrombosis has been reported after treatment with immune globulin products. In general, patients at greatest risk of thromboembolic events are those of advanced age, prolonged immobilization, hypercoagulable conditions, history of venous or arterial thrombosis, use of estrogens, indwelling central vascular catheters, hyperviscosity, and cardiovascular risk factors. Thrombosis may occur in the absence of known risk factors; therefore, it is recommended that patients treated with these agents should be monitored for signs and symptoms of thrombosis and assess blood viscosity in patients at risk. Consider baseline assessment of blood viscosity in patients at risk for hyperviscosity.
Hyponatremia
Major:
Polygam S/D
The immune globulin intravenous in Polygam S/D has a major potential interaction with Hyponatremia.
Thrombosis has been reported after treatment with immune globulin products. In general, patients at greatest risk of thromboembolic events are those of advanced age, prolonged immobilization, hypercoagulable conditions, history of venous or arterial thrombosis, use of estrogens, indwelling central vascular catheters, hyperviscosity, and cardiovascular risk factors. Thrombosis may occur in the absence of known risk factors; therefore, it is recommended that patients treated with these agents should be monitored for signs and symptoms of thrombosis and assess blood viscosity in patients at risk. Consider baseline assessment of blood viscosity in patients at risk for hyperviscosity.
Polycythemia
Major:
Polygam S/D
The immune globulin intravenous in Polygam S/D has a major potential interaction with Polycythemia.
Thrombosis has been reported after treatment with immune globulin products. In general, patients at greatest risk of thromboembolic events are those of advanced age, prolonged immobilization, hypercoagulable conditions, history of venous or arterial thrombosis, use of estrogens, indwelling central vascular catheters, hyperviscosity, and cardiovascular risk factors. Thrombosis may occur in the absence of known risk factors; therefore, it is recommended that patients treated with these agents should be monitored for signs and symptoms of thrombosis and assess blood viscosity in patients at risk. Consider baseline assessment of blood viscosity in patients at risk for hyperviscosity.
Renal Dysfunction
Major:
Polygam S/D
The immune globulin intravenous in Polygam S/D has a major potential interaction with Renal Dysfunction.
Renal abnormalities such as acute tubular necrosis, proximal tubular nephropathy, osmotic nephrosis, including acute renal dysfunction/failure and death have been reported after immune globulin intravenous (IGIV) products. Cases of renal dysfunction and acute renal failure occur more commonly in patients receiving IGIV products containing sucrose as a stabilizer. Ensure that patients are not volume-depleted before administering these agents and assess renal function, including measurement of blood urea nitrogen (BUN) and serum creatinine, before initiating the infusion and at appropriate intervals thereafter. If renal function deteriorates, consider discontinuation of the product. Periodic monitoring of renal function and urine output is important in patients at increased risk of developing acute renal failure. Administer these agents at the minimum dose and rate of infusion practicable in patients at risk for renal dysfunction or failure.
Sepsis
Major:
Polygam S/D
The immune globulin intravenous in Polygam S/D has a major potential interaction with Sepsis.
Renal abnormalities such as acute tubular necrosis, proximal tubular nephropathy, osmotic nephrosis, including acute renal dysfunction/failure and death have been reported after immune globulin intravenous (IGIV) products. Cases of renal dysfunction and acute renal failure occur more commonly in patients receiving IGIV products containing sucrose as a stabilizer. Ensure that patients are not volume-depleted before administering these agents and assess renal function, including measurement of blood urea nitrogen (BUN) and serum creatinine, before initiating the infusion and at appropriate intervals thereafter. If renal function deteriorates, consider discontinuation of the product. Periodic monitoring of renal function and urine output is important in patients at increased risk of developing acute renal failure. Administer these agents at the minimum dose and rate of infusion practicable in patients at risk for renal dysfunction or failure.
More resources
Antioxidant Formula
A total of 112 drugs are known to interact with Antioxidant Formula.
- Antioxidant formula is in the drug class vitamin and mineral combinations.
- Antioxidant formula is used to treat Vitamin/Mineral Supplementation and Deficiency.
Polygam S/D
A total of 108 drugs are known to interact with Polygam S/D.
- Polygam s/d is in the drug class immune globulins.
- Polygam s/d is used to treat Primary Immunodeficiency Syndrome.
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.