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Drug Interactions between Antabuse and Paral

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

paraldehyde disulfiram

Applies to: Paral (paraldehyde) and Antabuse (disulfiram)

Using disulfiram together with paraldehyde is not recommended. Combining these drugs may trigger a reaction similar to the disulfiram reaction, which includes unpleasant side effects such as flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion. More severe reactions may include heart attack, heart failure, unconsciousness, and convulsions. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Major

disulfiram food

Applies to: Antabuse (disulfiram)

You should not drink alcoholic beverages or use medicines that contain ethanol during treatment with disulfiram. This can cause flushing, nausea and vomiting, blurred vision, shortness of breath, rapid heart beat, and low blood pressure. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor.

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Moderate

paraldehyde food

Applies to: Paral (paraldehyde)

Alcohol can increase the nervous system side effects of paraldehyde such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with paraldehyde. Do not use more than the recommended dose of paraldehyde, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer