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Drug interactions between amphotericin b lipid complex and plazomicin

Results for the following 2 drugs:
amphotericin b lipid complex
plazomicin

Interactions between your drugs

Moderate

amphotericin B lipid complex plazomicin

Applies to: amphotericin b lipid complex and plazomicin

Consumer information for this interaction is not currently available.

MONITOR: The potential nephrotoxicity associated with amphotericin B and aminoglycosides may be additive.

MANAGEMENT: Just before the start and just before the end of each amphotericin infusion, hydration of the patient with 500 mL of normal saline may be helpful. The patient's renal function should be monitored frequently during therapy.

References

  1. Churchill DN, Seely J "Nephrotoxicity associated with combined gentamicin - amphotericin B therapy." Nephron 19 (1977): 176-81
  2. "Product Information. Arikayce (amikacin liposome)." Insmed Incorporated, Bridgewater, NJ.
  3. "Product Information. Abelcet (amphotericin B)." Liposome Company Inc, The, Princeton, NJ.

Drug and food interactions

No results found in our database - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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