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Drug Interactions between amitriptyline and cimetidine

This report displays the potential drug interactions for the following 2 drugs:

  • amitriptyline
  • cimetidine

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Interactions between your drugs

Moderate

cimetidine amitriptyline

Applies to: cimetidine and amitriptyline

Using cimetidine together with amitriptyline can increase the levels of amitriptyline. Contact your doctor if you experience excessive amitriptyline effects. This can include dry mouth, blurry vision, irregular or fast heartbeat, constipation, urinary retention, or extreme drowsiness. This can also cause dizziness or feeling like you might pass out, especially when getting up from a sitting or lying position. You may need a dose adjustment or special tests to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

No interactions were found. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.