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Drug Interactions between alvimopan and PC-CAP

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

propoxyphene alvimopan

Applies to: PC-CAP (aspirin / caffeine / propoxyphene) and alvimopan

Using alvimopan together with propoxyphene is not recommended. This can cause side effects such as abdominal pain, nausea, vomiting, and diarrhea. The use of alvimopan is discouraged if you have received propoxyphene for more than 7 consecutive days immediately prior to alvimopanadministration. Caution is advised if you have received more than 3 doses of propoxyphene within the week prior to surgery. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Minor

aspirin caffeine

Applies to: PC-CAP (aspirin / caffeine / propoxyphene) and PC-CAP (aspirin / caffeine / propoxyphene)

Information for this minor interaction is available on the professional version.

Drug and food interactions

Major

propoxyphene food

Applies to: PC-CAP (aspirin / caffeine / propoxyphene)

Do not use alcohol or medications that contain alcohol while you are receiving treatment with propoxyphene. This may increase nervous system side effects such as drowsiness, dizziness, lightheadedness, difficulty concentrating, and impairment in thinking and judgment. In severe cases, low blood pressure, respiratory distress, fainting, coma, or even death may occur. Do not use more than the recommended dose of propoxyphene, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.

Moderate

aspirin food

Applies to: PC-CAP (aspirin / caffeine / propoxyphene)

Ask your doctor before using aspirin together with ethanol (alcohol). Do not drink alcohol while taking aspirin. Alcohol can increase your risk of stomach bleeding caused by aspirin. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Minor

caffeine food

Applies to: PC-CAP (aspirin / caffeine / propoxyphene)

Information for this minor interaction is available on the professional version.

Minor

alvimopan food

Applies to: alvimopan

Information for this minor interaction is available on the professional version.

Minor

aspirin food

Applies to: PC-CAP (aspirin / caffeine / propoxyphene)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer