Can you take AlphaBath with Mavorixafor?
1 drug interaction and 10 additional warnings found for the following 2 drugs:
- AlphaBath (lanolin/mineral oil topical)
- mavorixafor
Drug interactions
Moderate drug interactions
Moderate:
mineral oil mavorixafor
Applies to: AlphaBath (lanolin / mineral oil topical) and mavorixafor
Mavorixafor can cause an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect.
The risk is increased if you have:
- a heart condition called congenital long QT syndrome
- other cardiac diseases
- conduction abnormalities
- electrolyte disturbances, such as low blood levels of magnesium or potassium
These electrolyte disturbances can occur with bowel cleansing preparations or excessive use of medications that have a laxative effect, such as mineral oil.
Do not exceed the dose and duration recommended on the product label or prescribed by your doctor.
You should seek immediate medical attention if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications, whether taken together or separately.
In addition, you should let your doctor know if you experience signs and symptoms of low magnesium or potassium blood level such as:
- weakness
- tiredness
- drowsiness
- dizziness
- confusion
- tingling
- numbness
- muscle pain
- cramps
- nausea
- vomiting
It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Food/lifestyle interactions
Major food/lifestyle interactions
Major:
mavorixafor Food/Lifestyle
Applies to: mavorixafor
Mavorixafor should be taken on an empty stomach after an overnight fast, 30 minutes before food.
Do not consume grapefruit products during treatment with mavorixafor unless otherwise directed by your doctor.
Grapefruit juice can increase the blood levels and adverse effects of mavorixafor, increasing the risk of experiencing a change in the electrical activity of your heart called QT prolongation, which can result in irregular heartbeats that can be life-threatening.
You should seek immediate medical attention if you experience an irregular heartbeat or feel dizzy, lightheaded, or faint during treatment.
Speak with your doctor or healthcare provider if you have any questions. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Moderate food/lifestyle interactions
Moderate:
mineral oil multivitamins with minerals
Applies to: AlphaBath (lanolin / mineral oil topical)
Using mineral oil together with multivitamins with minerals may decrease the effects of multivitamins with minerals.
Multivitamins with minerals should be administered at least 1 to 2 hours before or 4 to 6 hours after mineral oil.
This interaction does not apply to topical mineral oil.
If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications.
It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Disease interactions
8 potential interactions Applies to: 8 conditions, including Hypokalemia, Inflammatory Bowel Disease, Liver Disease, Long QT Syndrome, and Bleeding Disorder.
Appendicitis
Major:
AlphaBath
The mineral oil in AlphaBath has a major potential interaction with Appendicitis.
The use of stimulant laxatives is contraindicated in patients with or who may have acute surgical abdomen or appendicitis. These patients may be candidates for emergency surgery. Stimulant laxatives should also not be administered to patients with abdominal pain, particularly if the cause has not been determined.
Bleeding Disorder
Major:
AlphaBath
The mineral oil in AlphaBath has a major potential interaction with Bleeding Disorder.
The use of stimulant laxatives is contraindicated in patients with anal or rectal fissures. These preparations may cause irritation, burning sensation, and proctitis.
Gastrointestinal Obstruction
Major:
AlphaBath
The mineral oil in AlphaBath has a major potential interaction with Gastrointestinal Obstruction.
The use of laxatives is contraindicated in patients with intestinal obstruction disorders. Patients with intestinal obstruction disorders may need their underlying condition treated to correct the constipation. Some laxatives require reduction in the colon to their active form to be effective which may be a problem in patients with intestinal obstruction.
Hypokalemia
Moderate:
mavorixafor
Mavorixafor has a moderate potential interaction with Hypokalemia.
Mavorixafor causes concentration-dependent QTc interval prolongation. Correct any modifiable risk factors for QTc prolongation (e.g., hypokalemia), assess QTc at baseline and monitor during treatment as clinically indicated.
Inflammatory Bowel Disease
Major:
AlphaBath
The mineral oil in AlphaBath has a major potential interaction with Inflammatory Bowel Disease.
The use of laxatives is contraindicated in patients with inflammatory bowel disease. Patients with inflammatory bowel disease may experience colonic perforation with use of stimulant laxatives.
Liver Disease
Moderate:
mavorixafor
Mavorixafor has a moderate potential interaction with Liver Disease.
Mavorixafor is not recommended in patients with moderate to severe liver dysfunction.
Long QT Syndrome
Moderate:
mavorixafor
Mavorixafor has a moderate potential interaction with Long QT Syndrome.
Mavorixafor causes concentration-dependent QTc interval prolongation. Correct any modifiable risk factors for QTc prolongation (e.g., hypokalemia), assess QTc at baseline and monitor during treatment as clinically indicated.
Renal Dysfunction
Moderate:
mavorixafor
Mavorixafor has a moderate potential interaction with Renal Dysfunction.
Mavorixafor is not recommended in patients with severe renal impairment and end stage renal disease.
Report options
More resources
AlphaBath
A total of 262 drugs are known to interact with AlphaBath.
- Alphabath is in the drug class topical emollients.
mavorixafor
A total of 652 drugs are known to interact with mavorixafor.
- Mavorixafor is in the drug class other immunostimulants.
- Mavorixafor is used to treat WHIM Syndrome.
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.