Drug Interactions between Allegra-D 12 Hour and futibatinib

Grapefruit juice can increase the blood levels of futibatinib. This may increase side effects including dry or inflamed eyes, inflamed cornea, increased tears, disorder of the retina, high phosphate levels in your blood, redness, swelling, peeling or tenderness, mainly on the hands or feet, nails separating from the bed or poor formation of the nail, urinary tract infection, constipation, diarrhea, dry mouth, abdominal pain, fatigue, muscle and joint pain, decreased levels of blood cells (white blood cells, red blood cells, and platelets), and changes in liver function blood tests. You should avoid the consumption of grapefruit and grapefruit juice during treatment with futibatinib. Be sure to take the medication at approximately the same time every day to maintain consistent blood levels and effects. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Consuming large amounts of certain fruit juices, including grapefruit, orange and apple, may decrease the levels of fexofenadine in your body. Fexofenadine should be taken with water and refrain from drinking large amounts of grapefruit, orange, or apple juice. This will make it easier for your body to absorb the medication.

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Both pseudoephedrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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