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Drug interactions between aliskiren / amlodipine / hydrochlorothiazide and B-Nexa

Results for the following 2 drugs:
aliskiren/amlodipine/hydrochlorothiazide
B-Nexa (calcium/folic acid/ginger/pyridoxine)

Interactions between your drugs

Moderate

amLODIPine calcium phosphate, tribasic

Applies to: aliskiren / amlodipine / hydrochlorothiazide and B-Nexa (calcium / folic acid / ginger / pyridoxine)

Using amLODIPine together with calcium phosphate, tribasic can decrease the effects of amLODIPine. Talk with your doctor before using amLODIPine and calcium phosphate, tribasic together. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

hydroCHLOROthiazide calcium phosphate, tribasic

Applies to: aliskiren / amlodipine / hydrochlorothiazide and B-Nexa (calcium / folic acid / ginger / pyridoxine)

Using hydroCHLOROthiazide together with calcium phosphate, tribasic can cause your blood calcium levels to become too high. Contact your doctor if you experience symptoms such as dizziness, drowsiness, weakness, lethargy, headache, nausea, vomiting, or seizures. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

aliskiren food

Applies to: aliskiren / amlodipine / hydrochlorothiazide

Food can affect the absorption of aliskiren from the intestine. Therefore, you should take aliskiren at the same time each day exactly as prescribed by your doctor. You may take aliskiren with or without food, but take it the same way every time. This will help keep blood levels and effects of the medication steady. You should avoid drinking orange, apple, or grapefruit juice as much as possible during treatment with aliskiren. Studies have shown that drinking these juices regularly or within a short period before or after a dose of aliskiren can interfere with the absorption of the medication.

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Minor

amLODIPine food

Applies to: aliskiren / amlodipine / hydrochlorothiazide

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

For clinical details see professional interaction data.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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