Drug Interactions between Aler-Tab and letibotulinumtoxinA
This report displays the potential drug interactions for the following 2 drugs:
- Aler-Tab (diphenhydramine)
- letibotulinumtoxinA
Interactions between your drugs
diphenhydrAMINE letibotulinumtoxinA
Applies to: Aler-Tab (diphenhydramine) and letibotulinumtoxinA
Consumer information for this interaction is not currently available.
MONITOR: Use of anticholinergic drugs after administration of botulinum toxin may potentiate systemic anticholinergic effects such as dry mouth, blurred vision, and urinary disorders. Botulinum toxin inhibits the release of acetylcholine from peripheral cholinergic nerve endings, thus additive or synergistic anticholinergic effects may occur when these agents are used together.
MANAGEMENT: Patients should be advised that systemic anticholinergic side effects such as dry mouth, blurred vision, and urinary disorders may increase if agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic antidepressants; disopyramide) are used after administration of botulinum toxin.
References
- "Product Information. Myobloc (rimabotulinumtoxinB)." Elan Pharmaceuticals PROD
- "Product Information. Dysport (abobotulinumtoxinA)." Tercica Inc PROD
- "Product Information. Botox (onabotulinumtoxinA)." Allergan Inc PROD
- "Product Information. Xeomin (incobotulinumtoxinA)." Merz Pharmaceuticals (2022):
- "Product Information. Jeuveau (prabotulinumtoxinA)." Evolus, Inc. (2022):
- "Product Information. Daxxify (daxibotulinumtoxinA)." Revance Therapeutics, Inc. 1 (2022):
- "Product Information. Letybo (letibotulinumtoxinA)." CROMA Australia Pty Ltd 1 (2022):
- "Product Information. Letybo (letibotulinumtoxinA)." Hugel Aesthetics (2024):
Drug and food interactions
diphenhydrAMINE food
Applies to: Aler-Tab (diphenhydramine)
Ask your doctor before using diphenhydrAMINE together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking diphenhydrAMINE. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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