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Drug Interactions between AirDuo Respiclick and rasagiline

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

salmeterol rasagiline

Applies to: AirDuo Respiclick (fluticasone / salmeterol) and rasagiline

Using salmeterol together with rasagiline may increase cardiovascular side effects such as heart palpitations, chest pain, increased heart and pulse rates, and blood pressure elevations. The risk exists even when salmeterol or similar medications are given by oral inhalation directly into the lungs, and more so if these products are overused. Talk to your doctor before using these medications if you have a history of heart disease or high blood pressure. Depending on your condition, it may be preferable to wait at least 14 days after you are off rasagiline before you start using salmeterol. Do not exceed the dose and frequency of use of salmeterol recommended on the product label or prescribed by your doctor. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

fluticasone salmeterol

Applies to: AirDuo Respiclick (fluticasone / salmeterol) and AirDuo Respiclick (fluticasone / salmeterol)

Information for this minor interaction is available on the professional version.

Drug and food interactions

Moderate

rasagiline food

Applies to: rasagiline

Rasagiline may be taken with or without food. There is no need to avoid most foods and beverages during treatment with rasagiline, as long as you are not receiving more than 1 mg per day of the medication. However, certain foods such as some of the aged cheeses (for example, Boursault, Liederkrantz, Mycella, and Stilton) may contain very high amounts of tyramine and should generally be avoided if possible. Consumption of very high levels of tyramine (greater than 150 mg) while on rasagiline treatment may lead to dangerous increases in your blood pressure, a condition known as hypertensive crisis. Talk to your doctor or pharmacist if you are uncertain about what foods, if any, to avoid. You should seek immediate medical attention if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting during treatment with rasagiline, as these may be signs and symptoms of a hypertensive crisis. It is important to tell your doctor about all other medications you use, including vitamins and herbs, since some medications may increase the blood levels of rasagiline and possibly lead to interactions with tyramine-rich foods. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.