Drug Interactions between Advil Cold and Sinus and caffeine / pheniramine / phenylephrine / sodium citrate / sodium salicylate
This report displays the potential drug interactions for the following 2 drugs:
- Advil Cold and Sinus (ibuprofen/pseudoephedrine)
- caffeine/pheniramine/phenylephrine/sodium citrate/sodium salicylate
Interactions between your drugs
phenylephrine pseudoephedrine
Applies to: caffeine / pheniramine / phenylephrine / sodium citrate / sodium salicylate and Advil Cold and Sinus (ibuprofen / pseudoephedrine)
Both phenylephrine and pseudoephedrine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
phenylephrine caffeine
Applies to: caffeine / pheniramine / phenylephrine / sodium citrate / sodium salicylate and caffeine / pheniramine / phenylephrine / sodium citrate / sodium salicylate
Both phenylephrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
pseudoephedrine caffeine
Applies to: Advil Cold and Sinus (ibuprofen / pseudoephedrine) and caffeine / pheniramine / phenylephrine / sodium citrate / sodium salicylate
Both pseudoephedrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
pseudoephedrine sodium citrate
Applies to: Advil Cold and Sinus (ibuprofen / pseudoephedrine) and caffeine / pheniramine / phenylephrine / sodium citrate / sodium salicylate
Using pseudoephedrine together with sodium citrate may increase the effects of pseudoephedrine. Contact your doctor if you experience tremor, anxiety, insomnia, irritability, or nervousness. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
sodium salicylate sodium citrate
Applies to: caffeine / pheniramine / phenylephrine / sodium citrate / sodium salicylate and caffeine / pheniramine / phenylephrine / sodium citrate / sodium salicylate
Using sodium citrate together with sodium salicylate may decrease the effects of sodium salicylate. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
pheniramine food
Applies to: caffeine / pheniramine / phenylephrine / sodium citrate / sodium salicylate
Alcohol can increase the nervous system side effects of pheniramine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with pheniramine. Do not use more than the recommended dose of pheniramine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
ibuprofen food
Applies to: Advil Cold and Sinus (ibuprofen / pseudoephedrine)
Ask your doctor before using ibuprofen together with ethanol (alcohol). Do not drink alcohol while taking ibuprofen. Alcohol can increase your risk of stomach bleeding caused by ibuprofen. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
phenylephrine food
Applies to: caffeine / pheniramine / phenylephrine / sodium citrate / sodium salicylate
Both phenylephrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
pseudoephedrine food
Applies to: Advil Cold and Sinus (ibuprofen / pseudoephedrine)
Both pseudoephedrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
caffeine food
Applies to: caffeine / pheniramine / phenylephrine / sodium citrate / sodium salicylate
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.
Nonsteroidal anti-inflammatories
Therapeutic duplication
The recommended maximum number of medicines in the 'nonsteroidal anti-inflammatories' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'nonsteroidal anti-inflammatories' category:
- Advil Cold and Sinus (ibuprofen/pseudoephedrine)
- caffeine/pheniramine/phenylephrine/sodium citrate/sodium salicylate
Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.
Decongestants
Therapeutic duplication
The recommended maximum number of medicines in the 'decongestants' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'decongestants' category:
- Advil Cold and Sinus (ibuprofen/pseudoephedrine)
- caffeine/pheniramine/phenylephrine/sodium citrate/sodium salicylate
Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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