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Drug Interactions between Adeno-jec and disopyramide

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

adenosine disopyramide

Applies to: Adeno-jec (adenosine) and disopyramide

Before getting treatment with adenosine, let your doctor know if you are currently using disopyramide. Combining these medications can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

adenosine food

Applies to: Adeno-jec (adenosine)

Adenosine is used for heart imaging in the hospital or clinic setting. Caffeine should be avoided for 12 to 24 hours before adenosine administration. Avoid drinks, foods, or diet pills that contain caffeine, such as coffee, tea, cola, and chocolate. Taking a stimulant together with adenosine can increase your risk of unpleasant side effects.

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Moderate

disopyramide food

Applies to: disopyramide

Grapefruit juice may increase the blood levels of certain medications such as disopyramide. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with disopyramide. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

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Moderate

adenosine food

Applies to: Adeno-jec (adenosine)

Ask your doctor before using adenosine together with caffeine. Using these medications together can decrease the effects of adenosine. It is recommended that caffeine including caffeine be avoided for 12 to 24 hours before adenosine administration. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

disopyramide food

Applies to: disopyramide

Information for this minor interaction is available on the professional version.

Minor

adenosine food

Applies to: Adeno-jec (adenosine)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Antiarrhythmics

Therapeutic duplication

The recommended maximum number of medicines in the 'antiarrhythmics' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'antiarrhythmics' category:

  • Adeno-jec (adenosine)
  • disopyramide

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer