Drug Interactions between Actonel with Calcium and futibatinib
This report displays the potential drug interactions for the following 2 drugs:
- Actonel with Calcium (calcium carbonate/risedronate)
- futibatinib
Interactions between your drugs
calcium carbonate risedronate
Applies to: Actonel with Calcium (calcium carbonate / risedronate) and Actonel with Calcium (calcium carbonate / risedronate)
Risedronate and calcium carbonate should not be taken orally at the same time. Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of risedronate into the bloodstream and reduce its effectiveness. You should take calcium carbonate at least 30 minutes after the risedronate dose. Talk to a healthcare professional if you are not sure whether a product contains something that could potentially interact with your medication or if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
risedronate futibatinib
Applies to: Actonel with Calcium (calcium carbonate / risedronate) and futibatinib
Using risedronate together with futibatinib may increase the levels of phosphate in the blood, which may increase your risk of high phosphate levels (hyperphosphatemia), and a buildup of minerals such as calcium in different tissues in your body. Your doctor will check your blood phosphate level regularly when your first start treatment with futibatinib and regularly throughout treatment. They may recommend changes in your diet, phosphate-lowering therapy, and/or change your dose of futibatinib if necessary. Talk to your doctor if you have any questions or concerns. Contact your doctor as soon as possible if you develop signs and symptoms of high phosphate levels in the blood (hyperphosphatemia) such as muscle cramps, convulsions, tingling or numbness around the mouth, and bone pain. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
futibatinib food
Applies to: futibatinib
Grapefruit juice can increase the blood levels of futibatinib. This may increase side effects including dry or inflamed eyes, inflamed cornea, increased tears, disorder of the retina, high phosphate levels in your blood, redness, swelling, peeling or tenderness, mainly on the hands or feet, nails separating from the bed or poor formation of the nail, urinary tract infection, constipation, diarrhea, dry mouth, abdominal pain, fatigue, muscle and joint pain, decreased levels of blood cells (white blood cells, red blood cells, and platelets), and changes in liver function blood tests. You should avoid the consumption of grapefruit and grapefruit juice during treatment with futibatinib. Be sure to take the medication at approximately the same time every day to maintain consistent blood levels and effects. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
calcium carbonate food
Applies to: Actonel with Calcium (calcium carbonate / risedronate)
Calcium absorption may be increased by taking it with food. However, foods high in oxalic acid (spinach or rhubarb), or phytic acid (bran and whole grains) may decrease calcium absorption. Calcium may be taken with food to increase absorption. Consider spacing calcium administration for at least 2 hours before or after consuming foods high in oxalic acid or phytic acid. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
risedronate food
Applies to: Actonel with Calcium (calcium carbonate / risedronate)
Food may reduce the absorption of risedronate, which may lead to lower blood levels of the medication and possibly reduced effectiveness. You should take risedronate first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medication. Take each dose with a full glass (6 to 8 ounces) of water, and use only plain water (not mineral or vitamin water). Do not take risedronate if you cannot sit upright or stand for at least 30 minutes. Because risedronate can cause irritation and ulcer in the stomach or esophagus (the tube that connects your mouth and stomach), you will need to stay upright for at least 30 minutes after taking this medication. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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